Monographs
In collaboration with toxicology labs, medical examiner and coroner offices, crime laboratories, clinical partners, and the National Institute of Justice (NIJ), the CFSRE is documenting the first reports of NPS in the United States and around the world through analysis of toxicology samples and drug materials. These reports, called “new drug monographs”, are generated using comprehensive analytical techniques (e.g. GC-MS, LC-QTOF-MS, NMR, FTIR) and include available information about the new drug(s) identified at the time of reporting, as well as the analytical data generated during testing. These reports are intended to assist with the rapid identification of NPS in forensic casework and related disciplines, and should not be used for confirmatory purposes alone.The data in our new drug monographs are not externally peer-reviewed, however, the data are reviewed and interpreted internally by our leading scientific staff. All identifications are required to meet minimum criteria during review (e.g., mass error <5 ppm, retention within 0.05 minutes for GC-MS or 0.35 minutes for LC-QTOF-MS, expected vs. acquired fragmentation pattern match, etc.), depending on the analyses performed and the availability of a standard reference material(s). Contact our program for more information about our review and reporting processes.
- Download the GCMS Library Database (Last updated: 06/16/2022) – Readable in Agilent MSD ChemStation
- Download the LC-QTOF-MS Library Database (Last updated: 08/17/2023) – Readable with SCIEX LibraryView
Date | Class | CompoundStructure | Formula | MW | [M+] | [M+H]+ | | |
---|---|---|---|---|---|---|---|---|
09/04/2024 | Stimulant | N-Isopropyl Butylone | C14H19NO3 | 249.3 | 249 | 250.1438 | ||
09/03/2024 | Miscellaneous | BTMPS | C28H52N2O4 | 480.7 | 480 | 481.4000 | ||
08/30/2024 | Opioid | ortho-Methyl Boc-4-AP | C17H26N2O2 | 290.4 | 290 | 291.2067 | ||
08/29/2024 | Opioid | Methylenedioxynitazene | C21H24N4O4 | 369.4 | 396 | 397.1870 | ||
08/28/2024 | Benzodiazepine | Desalkylquazepam | C15H10ClFN2S | 304.8 | 304 | 305.0310 | ||
08/27/2024 | Stimulant | Chloromethcathinone | C10H12ClNO | 197.7 | 197 | 198.0680 | ||
08/26/2024 | Opioid | 5-Methyl Etodesnitazene | C23H31N3O | 365.5 | 365 | 366.2540 | ||
08/23/2024 | Opioid | 5,6-Dichloro Desmethylchlorphine | C19H18Cl3N3O | 410.7 | 409 | 410.0588 | ||
08/22/2024 | Hallucinogen | 3-Methyl-PCP | C18H27N | 257.4 | 257 | 258.2216 | ||
08/21/2024 | Opioid | N-Phenethyl Noroxymorphone | C24H25NO4 | 391.5 | 391 | 392.1856 | ||
08/20/2024 | Stimulant | Bromantane | C16H20BrN | 306.2 | 305 | 306.0852 | ||
08/19/2024 | Cannabinoid | AB-CHMINACA | C20H28N4O2 | 356.5 | 356 | 357.2285 | ||
06/20/2024 | Cannabinoid | MMB-4en-PINACA | C19H25N3O3 | 343.42 | 343 | 344.1969 | ||
12/20/2023 | Opioid | ortho-Methylfentanyl | C23H30N2O | 350.50 | 350 | 351.2431 | ||
11/30/2023 | Opioid | N-Desethyl Etonitazene | C20H24N4O3 | 368.4 | 368 | 369.1921 | ||
11/29/2023 | Benzodiazepine | Rilmazafone | C21H20Cl2N6O3 | 475.3 | 474 | 475.1047 | ||
11/28/2023 | Cannabinoid | MDMB-ICA | C16H20N2O3 | 288.3 | 288 | 289.1547 | ||
11/28/2023 | Cannabinoid | MDMB-PICA | C21H30N2O3 | 358.5 | 358 | 359.2329 | ||
11/27/2023 | Miscellaneous | Medetomidine | C13H16N2 | 200.3 | 200 | 201.1386 | ||
11/22/2023 | Cannabinoid | NMDMSB | C20H19NO4S | 369.4 | 369 | 370.1108 | ||
11/21/2023 | Cannabinoid | MDMB-5Me-INACA | C16H21N3O3 | 303.4 | 303 | 304.1656 | ||
11/20/2023 | Benzodiazepine | 4'-Chlorodiazepam | C16H12Cl2N2O | 319.2 | 318 | 319.0399 | ||
06/28/2023 | Cannabinoid | CHO-4'Me-5'Br-FUBOXPYRA | C20H22BrFN2O2 | 421.30 | 420 | 421.0921 | ||
06/27/2023 | Cannabinoid | MDMB-BINACA | C19H27N3O3 | 345.43 | 345 | 346.2125 | ||
06/26/2023 | Cannabinoid | MDMB-INACA | C15H19N3O3 | 289.33 | 289 | 290.1499 | ||
06/23/2023 | Opioid | N-Pyrrolidino Metonitazene | C21H24N4O3 | 380.44 | 380 | 381.1921 | ||
06/22/2023 | Opioid | N-Pyrrolidino Protonitazene | C23H28N4O3 | 408.49 | 408 | 409.2234 | ||
06/21/2023 | Hallucinogen | 25B-NBOH | C17H20BrNO3 | 366.25 | 365 | 366.0699 | ||
06/20/2023 | Stimulant | 4-Methylmethylphenidate | C15H21NO2 | 247.33 | 247 | 248.1645 | ||
05/01/2023 | Cannabinoid | ADB-5’Br-PINACA | C19H27BrN4O2 | 423.35 | 422 | 423.1390 | ||
12/30/2022 | Stimulant | Trimethoxyamphetamine | C12H19NO3 | 225.3 | 225 | 226.1438 | ||
12/19/2022 | Opioid | N-Desethyl Isotonitazene | C21H26N4O3 | 382.5 | 382 | 383.2078 | ||
12/16/2022 | Hallucinogen | Fluorexetamine (FXE) | C14H18FNO | 235.3 | 235 | 236.1445 | ||
12/15/2022 | Stimulant | Methylmethcathinone (MMC) | C11H15NO | 177.2 | 177 | 178.1226 | ||
12/14/2022 | Cannabinoid | ADB-INACA | C14H18N4O2 | 274.3 | 274 | 275.1503 | ||
12/13/2022 | Cannabinoid | CUMYL-TsINACA | C24H23N3O3S | 433.5 | 433 | 434.1533 | ||
12/09/2022 | Benzodiazepine | Desalkylgidazepam | C15H11BrN2O | 315.2 | 314 | 315.0128 | ||
12/08/2022 | Benzodiazepine | Fluetizolam | C17H15FN4S | 326.4 | 326 | 327.1074 | ||
12/07/2022 | Benzodiazepine | 4'Cl-Deschloroalprazolam | C17H13ClN4 | 308.8 | 308 | 309.0902 | ||
12/06/2022 | Benzodiazepine | Phenazolam | C17H12BrClN4 | 387.7 | 386 | 387.0007 | ||
08/31/2022 | Hallucinogen | Hydroxetamine (HXE) | C14H19NO2 | 233.3 | 233 | 234.1489 | ||
07/21/2022 | Stimulant | N-Propyl Butylone | C14H19NO3 | 249.3 | 249 | 250.1438 | ||
06/21/2022 | Cannabinoid | CH-FUBIATA | C23H25FN2O | 364.5 | 364 | 365.2024 | ||
06/09/2022 | Stimulant | N-Cyclohexyl Butylone | C17H23NO3 | 289.4 | 289 | 290.1751 | ||
05/26/2022 | Cannabinoid | ADB-5’Br-BINACA | C18H25BrN4O2 | 409.3 | 408 | 409.1234 | ||
05/19/2022 | Cannabinoid | BZO-4en-POXIZID | C20H19N3O2 | 333.4 | 333 | 334.1550 | ||
05/17/2022 | Cannabinoid | ADB-5Br-INACA | C14H17BrN4O2 | 353.2 | 352 | 353.0608 | ||
05/17/2022 | Cannabinoid | MDMB-5Br-INACA | C15H18BrN3O3 | 368.2 | 367 | 368.0604 | ||
05/09/2022 | Stimulant | N-Cyclohexyl Methylone | C16H21NO3 | 275.3 | 275 | 276.1594 | ||
04/29/2022 | Cannabinoid | CH-PIATA | C21H30N2O | 326.5 | 326 | 327.2431 | ||
03/14/2022 | Opioid | Dipyanone | C23H29NO | 335.5 | 335 | 336.2322 | ||
12/20/2021 | Cannabinoid | EDMB-PINACA | C21H31N3O3 | 373.5 | 373 | 374.2438 | ||
12/17/2021 | Stimulant | N,N-Dimethylpentylone | C14H19NO3 | 249.3 | 249 | 250.1438 | ||
12/16/2021 | Opioid | Napthyl-U-47700 | C20H26N2O | 310.4 | 310 | 311.2118 | ||
12/15/2021 | Hallucinogen | Tenocyclidine | C15H23NS | 249.4 | 249 | 250.1624 | ||
12/14/2021 | Opioid | Trifluoromethyl-U-47700 | C17H23F3N2O | 328.4 | 328 | 329.1835 | ||
11/22/2021 | Opioid | N-Piperidinyl Etonitazene | C23H28N4O3 | 408.5 | 408 | 409.2234 | ||
11/19/2021 | Cannabinoid | ADB-PHETINACA | C22H26N4O2 | 378.5 | 378 | 379.2129 | ||
11/18/2021 | Cannabinoid | BZO-CHMOXIZID | C22H23N3O2 | 361.4 | 361 | 362.1863 | ||
11/17/2021 | Cannabinoid | ADB-FUBIATA | C23H26FN3O2 | 395.5 | 395 | 396.2082 | ||
11/05/2021 | Benzodiazepine | Fluclotizolam | C15H10ClFN4S | 332.8 | 332 | 333.0372 | ||
10/19/2021 | Cannabinoid | 5F-BZO-POXIZID | C20H20FN3O2 | 353.4 | 353 | 354.1612 | ||
10/19/2021 | Cannabinoid | BZO-HEXOXIZID | C21H23N3O2 | 349.4 | 349 | 350.1863 | ||
10/19/2021 | Cannabinoid | BZO-POXIZID | C20H21N3O2 | 335.4 | 335 | 336.1707 | ||
09/22/2021 | Opioid | Metodesnitazene | C21H27N3O | 337.5 | 337 | 338.2227 | ||
06/29/2021 | Hallucinogen | 4-AcO-EPT | C17H24N2O2 | 288.4 | 288 | 289.1911 | ||
05/26/2021 | Opioid | Protonitazene | C23H30N4O3 | 410.5 | 410 | 411.2391 | ||
05/13/2021 | Opioid | N-Pyrrolidino Etonitazene | C22H26N4O3 | 394.5 | 394 | 395.2078 | ||
04/29/2021 | Cannabinoid | ADB-HEXINACA | C20H30N4O2 | 358.5 | 358 | 359.2442 | ||
04/23/2021 | Stimulant | Methylenedioxy-PV8 | C18H25NO3 | 303.4 | 303 | 304.1907 | ||
03/26/2021 | Opioid | Flunitazene | C20H23FN4O2 | 370.4 | 370 | 371.1878 | ||
03/04/2021 | Cannabinoid | ADB-4en-PINACA | C19H26N4O2 | 342.4 | 342 | 343.2129 | ||
02/23/2021 | Opioid | Etodesnitazene | C22H29N3O | 351.5 | 351 | 352.2383 | ||
02/16/2021 | Benzodiazepine | Deschloroetizolam | C17H16N4S | 308.4 | 308 | 309.1168 | ||
02/04/2021 | Hallucinogen | Cl-PCP | C17H24ClN | 277.8 | 277 | 278.1670 | ||
02/04/2021 | Hallucinogen | F-PCP | C17H24FN | 261.4 | 261 | 262.1966 | ||
01/27/2021 | Cannabinoid | 4F-ABINACA | C22H28FN3O | 369.5 | 369 | 370.2289 | ||
01/15/2021 | Opioid | Butonitazene | C24H32N4O3 | 424.5 | 424 | 425.2547 | ||
12/17/2020 | Opioid | Bromofentanyl | C22H27BrN2O | 415.4 | 414 | 415.1380 | ||
12/17/2020 | Opioid | Chlorofentanyl | C22H27ClN2O | 370.9 | 370 | 371.1885 | ||
12/17/2020 | Opioid | Fluorofentanyl | C22H27FN2O | 354.5 | 354 | 355.2180 | ||
12/10/2020 | Hallucinogen | MeO-PCE | C15H23NO | 233.4 | 233 | 234.1852 | ||
12/03/2020 | Cannabinoid | 5F-EDMB-PICA | C22H31FN2O3 | 390.5 | 390 | 391.2391 | ||
12/01/2020 | Stimulant | 4-Fluoro-3-Methyl-Alpha-PVP | C16H22FNO | 263.4 | 263 | 264.1758 | ||
11/18/2020 | Cannabinoid | ADB-BINACA | C18H26N4O2 | 330.4 | 330 | 331.2129 | ||
11/11/2020 | Opioid | AP-238 | C18H26N2O | 286.4 | 286 | 287.2118 | ||
08/11/2020 | Benzodiazepine | Adinazolam | C19H18ClN5 | 351.8 | 351 | 352.1323 | ||
07/30/2020 | Opioid | Metonitazene | C21H26N4O3 | 382.5 | 382 | 383.2078 | ||
07/17/2020 | Opioid | Brorphine | C20H22BrN3O | 400.3 | 399 | 400.1019 | ||
07/06/2020 | Benzodiazepine | Metizolam | C16H13ClN4S | 328.8 | 328 | 329.0622 | ||
07/01/2020 | Cannabinoid | 4F-MDMB-BICA | C20H27FN2O3 | 362.4 | 362 | 363.2078 | ||
06/15/2020 | Cannabinoid | 5F-EMB-PICA | C21H29FN2O3 | 376.5 | 376 | 377.2235 | ||
06/09/2020 | Stimulant | Hexylone | C14H19NO3 | 249.3 | 249 | 250.1438 | ||
05/29/2020 | Cannabinoid | 5F-CUMYL-PINACA | C22H26FN3O | 367.5 | 367 | 368.2133 | ||
05/27/2020 | Stimulant | alpha-PCYP | C18H25NO | 271.4 | 271 | 272.2009 | ||
05/07/2020 | Stimulant | 4F-Ethylphenidate | C15H20FNO2 | 265.3 | 265 | 266.1551 | ||
05/01/2020 | Benzodiazepine | Bromazolam | C17H13BrN4 | 353.2 | 352 | 353.0396 | ||
04/13/2020 | Stimulant | Methoxpropamine (MXPr) | C16H23NO2 | 261.4 | 261 | 262.1802 | ||
04/13/2020 | Opioid | para-Methyl AP-237 | C18H26N2O | 286.4 | 286 | 287.2118 | ||
03/24/2020 | Opioid | N-Ethyl-U-47700 | C17H24Cl2N2O | 343.3 | 342 | 343.1338 | ||
03/11/2020 | Opioid | 3,4-Difluoro-U-47700 | C16H22F2N2O | 296.4 | 296 | 297.1773 | ||
02/24/2020 | Stimulant | N-Ethyl Pentedrone | C13H19NO | 205.3 | 205 | 206.1539 | ||
12/12/2019 | Hallucinogen | 3-HO-PCE | C14H21NO | 219.3 | 219 | 220.1696 | ||
12/03/2019 | Stimulant | 4F-Pentedrone | C12H16FNO | 209.3 | 209 | 210.1289 | ||
11/26/2019 | Opioid | para-Methylcyclopropylfentanyl | C24H30N2O | 362.5 | 362 | 363.2431 | ||
11/22/2019 | Opioid | N-Methyl U-47931E | C16H23BrN2O | 339.3 | 338 | 339.1067 | ||
11/19/2019 | Opioid | Isotonitazene | C23H30N4O3 | 410.5 | 410 | 411.2391 | ||
11/15/2019 | Opioid | 2F-Viminol | C21H31FN2O | 346.5 | 346 | 347.2493 | ||
10/31/2019 | Stimulant | 3,4-Dichloromethylphenidate | C14H17Cl2NO2 | 302.2 | 301 | 302.0709 | ||
10/31/2019 | Stimulant | Isopropylphenidate | C16H23NO2 | 261.4 | 261 | 262.1802 | ||
10/11/2019 | Cannabinoid | MMB-4en-PICA | C20H26N2O3 | 342.4 | 342 | 343.2016 | ||
09/30/2019 | Stimulant | N-ethyl Heptedrone | C15H23NO | 233.4 | 233 | 234.1852 | ||
09/18/2019 | Opioid | Piperidylthiambutene | C17H21NS2 | 303.5 | 303 | 304.1188 | ||
09/16/2019 | Opioid | AP-237 | C17H24N2O | 272.4 | 272 | 273.1961 | ||
09/12/2019 | Cannabinoid | MDMB-4en-PINACA | C20H27N3O3 | 357.5 | 357 | 358.2125 | ||
07/03/2019 | Stimulant | N-butyl Hexedrone | C16H25NO | 247.4 | 247 | 248.2009 | ||
06/25/2019 | Benzodiazepine | Flualprazolam | C17H12ClFN4 | 326.8 | 326 | 327.0807 | ||
06/21/2019 | Opioid | 2-Methyl AP-237 | C18H26N2O | 286.4 | 286 | 287.2118 | ||
06/18/2019 | Miscellaneous | Furanyl UF-17 | C19H24N2O2 | 312.4 | 312 | 313.1910 | ||
06/18/2019 | Miscellaneous | UF-17 | C17H26N2O | 274.4 | 274 | 275.2118 | ||
06/04/2019 | Stimulant | Benzylone (BMDP) | C17H17NO3 | 283.3 | 283 | 284.1281 | ||
05/29/2019 | Hallucinogen | 4-HO-MET | C13H18N2O | 218.3 | 218 | 219.1492 | ||
05/16/2019 | Stimulant | N-butyl Pentylone | C16H23NO3 | 277.4 | 277 | 278.1751 | ||
04/30/2019 | Opioid | 2’,5’-Dimethoxyfentanyl | C24H32N2O3 | 396.5 | 396 | 397.2486 | ||
04/23/2019 | Opioid | para-Methoxyfuranylfentanyl | C25H28N2O3 | 404.5 | 404 | 405.2173 | ||
04/16/2019 | Hallucinogen | 1P-LSD | C23H29N3O2 | 379.5 | 379 | 380.2333 | ||
03/18/2019 | Stimulant | N,N-Diethyl Hexedrone | C16H25NO | 247.4 | 247 | 248.2009 | ||
03/11/2019 | Hallucinogen | 25C-NBOH | C17H20ClNO3 | 321.8 | 321 | 322.1204 | ||
03/06/2019 | Cannabinoid | APP-BINACA | C21H24N4O2 | 364.4 | 364 | 365.1972 | ||
02/12/2019 | Cannabinoid | 5F-MPP-PICA | C24H27FN2O3 | 410.5 | 410 | 411.2078 | ||
02/04/2019 | Hallucinogen | 4-Acetoxy-MALT | C16H20N2O2 | 272.3 | 272 | 273.1598 | ||
01/23/2019 | Opioid | Fluorofuranylfentanyl | C24H25FN2O2 | 392.5 | 392 | 393.1973 | ||
01/11/2019 | Cannabinoid | 4F-MDMB-BINACA | C19H26FN3O3 | 363.4 | 363 | 364.2031 | ||
01/03/2019 | Stimulant | 4-Fluoroethamphetamine | C11H16FN | 181.3 | 181 | 182.1340 | ||
12/19/2018 | Benzodiazepine | Nitrazolam | C17H13N5O2 | 319.3 | 319 | 320.1142 | ||
10/30/2018 | Stimulant | 4-CDMC | C11H14ClNO | 211.7 | 211 | 212.0837 | ||
10/30/2018 | Stimulant | alpha-PiHP | C16H23NO | 245.4 | 245 | 246.1852 | ||
10/30/2018 | Opioid | U-47931E | C15H21BrN2O | 325.2 | 324 | 325.0910 | ||
10/18/2018 | Cannabinoid | MFUBINAC | C16H13FN2O2 | 284.3 | 284 | 285.1034 | ||
10/05/2018 | Cannabinoid | 5Cl-AB-PINACA | C18H25ClN4O2 | 364.9 | 364 | 365.1739 | ||
10/05/2018 | Cannabinoid | 5F-AB-PFUPPYCA | C20H26F2N4O2 | 392.4 | 392 | 393.2097 | ||
10/05/2018 | Opioid Precursor | Despropionyl para-Fluorobenzylfentanyl | C18H21FN2 | 284.4 | 284 | 285.1762 | ||
10/05/2018 | Opioid Precursor | para-Fluorocyclopropylbenzylfentanyl | C22H25FN2O | 352.4 | 352 | 353.2024 | ||
09/04/2018 | Hallucinogen | 2F-Deschloroketamine | C13H16FNO | 221.3 | 221 | 222.1289 | ||
09/04/2018 | Stimulant | 3,4-Methylenedioxy-alpha-PHP | C17H23NO3 | 289.4 | 289 | 290.1751 | ||
09/04/2018 | Stimulant | Eutylone | C13H17NO3 | 235.3 | 235 | 236.1281 | ||
09/04/2018 | Opioid | Phenylfentanyl | C26H28N2O | 384.5 | 384 | 385.2274 | ||
08/06/2018 | Stimulant | Tertylone | C14H19NO3 | 249.3 | 249 | 250.1438 | ||
07/31/2018 | Cannabinoid | 5F-MDMB-PICA | C21H29FN2O3 | 376.5 | 376 | 377.2235 | ||
06/01/2018 | Hallucinogen | Deschloro-N-ethyl Ketamine | C14H19NO | 217.3 | 217 | 218.1539 | ||
05/18/2018 | Opioid | Isopropyl-U-47700 | C18H26Cl2N2O | 357.3 | 356 | 357.1495 | ||
05/18/2018 | Opioid | Methylenedioxy-U-47700 | C17H24N2O3 | 304.4 | 304 | 305.1860 | ||
05/04/2018 | Stimulant | 3,4-Dichloroethcathinone (DCEC) | C11H13Cl2NO | 246.1 | 245 | 246.0447 | ||
04/27/2018 | Opioid Precursor | Benzylfuranylfentanyl | C23H24N2O2 | 360.5 | 360 | 361.1911 | ||
04/19/2018 | Stimulant | N-ethyl Hexylone | C15H21NO3 | 263.3 | 263 | 264.1594 | ||
04/10/2018 | Cannabinoid | 5Br-AKB48 | C23H30BrN3O | 444.4 | 443 | 444.1645 | ||
04/10/2018 | Cannabinoid | 5Cl-AKB48 | C23H30ClN3O | 400.0 | 399 | 400.2150 | ||
04/10/2018 | Cannabinoid | 5F-EDMB-PINACA | C21H30FN3O3 | 391.5 | 391 | 392.2344 | ||
04/10/2018 | Opioid Precursor | N-methyl Norfentanyl | C15H22N2O | 246.4 | 246 | 247.1805 | ||
03/27/2018 | Opioid Precursor | Despropionyl 3-Methylfentanyl | C20H26N2 | 294.4 | 294 | 295.2169 | ||
03/27/2018 | Opioid Precursor | Despropionyl ortho-Methylfentanyl | C20H26N2 | 294.4 | 294 | 295.2169 | ||
03/27/2018 | Opioid | ortho-Methylmethoxyacetylfentanyl | C23H30N2O2 | 366.5 | 366 | 367.2380 | ||
03/26/2018 | Opioid | U-48800 | C17H24Cl2N2O | 343.3 | 342 | 343.1338 | ||
03/20/2018 | Cannabinoid | Adamantyl-CHMINACA | C25H33N3O | 391.6 | 391 | 392.2696 | ||
02/27/2018 | Hallucinogen | 25E-NBOH | C19H25NO3 | 315.4 | 315 | 316.1907 | ||
02/27/2018 | Stimulant | 4-MDEC | C14H21NO | 219.3 | 219 | 220.1696 | ||
02/27/2018 | Hallucinogen | N-Acetyl 25I-NBOMe | C20H24INO4 | 469.3 | 469 | 470.0823 |