MDMB-INACA

The following information was compiled in June 2023 and is subject to change as new research is conducted and as new information becomes available:

Description: MDMB-INACA is a synthetic cannabinoid precursor that can be used to produce MDMB-4en-PINACA, MDMB-BINACA, MDMB-PINACA, 4F-MDMB-BINACA, and other structurally related synthetic cannabinoids. To date, MDMB-INACA has appeared alongside MDMB-4en-PINACA and MDMB-BINACA in drug materials and/or toxicology samples tested by our laboratory in the United States. Synthetic cannabinoid precursors (e.g., ADB-INACA, MDMB-5’Br-INACA) began to appear after the implementation of a national class-wide synthetic cannabinoid scheduling action imposed by China in July 2021.

Sample Source: Drug material – United States (e.g., New York).

Sample Appearance: Drug material – impregnated paper.

Pharmacology: The activity and potency of MDMB-INACA are unknown; however, based on structurally similar synthetic cannabinoid precursors, MDMB-INACA is expected to be inactive or have low potency.

Toxicology: MDMB-INACA has been detected in seven toxicology cases at the CFSRE.

Drug Materials: MDMB-INACA has been detected in one drug material at the CFSRE.

Demographics / Geographics: Cases originated from three states, including Texas, New York, and Maryland. In death investigations, decedents were predominantly male, ranging in age from 20s-40s.

Legal Status: MDMB-INACA is not explicitly scheduled in the United States.

Class:

Cannabinoid

Appearance:

Paper

Formula:

C15H19N3O3

MW:

289.33

[M+]:

289

[M+H]+:

290.1499

IUPAC:

methyl 2-(1H-indazole-3-carbonylamino)-3,3-dimethyl-butanoate

Report Date:

June 26, 2023