N-Cyclohexyl Methylone

N-Cyclohexyl methylone is classified as a novel stimulant and substituted cathinone. Substituted cathinones are modified based on the structure of cathinone, an alkaloid found in the Khat plant. Novel stimulants have been reported to cause psychoactive effects similar to amphetamines. Novel stimulants have also caused adverse events, including deaths, as described in the literature. Structurally similar drugs include methylone and diethlyone (or N,N-diethyl methylone), among other beta-keto methylenedioxyamphetamine (or “-ylones”). Methylone is a Schedule I substance in the United States; N-cyclohexyl methylone is not explicitly scheduled.

N-Cyclohexyl methylone has been mentioned in online drug forums and appeared for sale on surface web gray market vendor sites under the name “cyputylone”. Scientific experts agree that the name “cyputylone” is not preferred due to nomenclature inconsistency and potential for confusion, and rather suggest the name “N-cyclohexyl methylone” be universally used instead.

Class:

Stimulant

Appearance:

(1) Ecstasy Tablet (2) Beige Crystalline Rock and Off-White Crystalline Powder

Formula:

C16H21NO3

MW:

275.3

[M+]:

275

[M+H]+:

276.1594

IUPAC:

1-(1,3-benzodioxol-5-yl)-2-(cyclohexylamino)propan-1-one

Report Date:

May 9, 2022