Chlorphine

The following information was compiled in December 2024 and is subject to change as new research is conducted and as new information becomes available:

Description: Chlorphine is a novel synthetic opioid bearing structural similarity to other benzimidazolones (e.g., brorphine, fluorphine). Chlorphine was first identified by our laboratory in August 2024 and confirmed using standard reference material.

Sample Source: Tapestry  in Collaboration with StreetCheck

Sample Appearance: White material

Pharmacology: In vitro pharmacological data available show that chlorphine is an agonist with high affinity for the mu-opioid receptor and has activity and potency similar to brorphine.1

Toxicology: Chlorphine has not been identified in toxicology cases to date at the CFSRE.

Drug Materials: Chlorphine has been detected in one drug material to date at the CFSRE.

Demographics / Geographics: The drug material positive for chlorphine originated from Connecticut and was identified alongside the novel synthetic opioid N-propionitrile chlorphine.

Legal Status: Chlorphine is not currently a scheduled drug in the United States.



Class:
Opioid
Appearance:
White material
Formula:
C20H22ClN3O
MW:
355.9
[M+]:
355
[M+H]+:
356.1524
IUPAC:
3-[1-[1-(4-chlorophenyl)ethyl]-4-piperidyl]-1H-benzimidazol-2-one
Report Date:
December 17, 2024
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