Chlorphine
The following information was compiled in December 2024 and is subject to change as new research is conducted and as new information becomes available:
Description: Chlorphine is a novel synthetic opioid bearing structural similarity to other benzimidazolones (e.g., brorphine, fluorphine). Chlorphine was first identified by our laboratory in August 2024 and confirmed using standard reference material.
Sample Source: Tapestry in Collaboration with StreetCheck
Sample Appearance: White material
Pharmacology: In vitro pharmacological data available show that chlorphine is an agonist with high affinity for the mu-opioid receptor and has activity and potency similar to brorphine.1
Toxicology: Chlorphine has not been identified in toxicology cases to date at the CFSRE.
Drug Materials: Chlorphine has been detected in one drug material to date at the CFSRE.
Demographics / Geographics: The drug material positive for chlorphine originated from Connecticut and was identified alongside the novel synthetic opioid N-propionitrile chlorphine.
Legal Status: Chlorphine is not currently a scheduled drug in the United States.
- Class:
- Opioid
- Appearance:
- White material
- Formula:
- C20H22ClN3O
- MW:
- 355.9
- [M+]:
- 355
- [M+H]+:
- 356.1524
- IUPAC:
- 3-[1-[1-(4-chlorophenyl)ethyl]-4-piperidyl]-1H-benzimidazol-2-one
- Report Date:
- December 17, 2024