4Cl-MDMB-BINACA

The following information was compiled in December 2024 and is subject to change as new research is conducted and as new information becomes available:

Description: 4Cl-MDMB-BINACA is a novel synthetic cannabinoid bearing structural similarity to 4F-MDMB-BINACA, MDMB-BINACA, and other synthetic cannabinoids. 4Cl-MDMB-BINACA was first detected in September 2024 by our laboratory and was confirmed in November 2024 after acquisition of standard reference material.

Sample Source: Center of Forensic & Digital Science Abu Dhabi Judicial Department

Sample Appearance: Bottle containing transparent liquid

Pharmacology: No information is available at this time for 4Cl-MDMB-BINACA; however, based on structural similarity to other indazole synthetic cannabinoids (i.e., 4F-MDMB-BINACA), 4Cl-MDMB-BINACA is assumed to be a potent CB₁ receptor agonist.¹

Toxicology: 4Cl-MDMB-BINACA has not been identified in toxicology cases to date at the CFSRE.

Drug Materials: 4Cl-MDMB-BINACA has been detected in one drug material to date at the CFSRE.

Demographics / Geographics: The drug material positive for 4Cl-MDMB-BINACA originated from Abu Dhabi and was identified alongside other synthetic cannabinoids (e.g., MDMB-BINACA, MDMB-INACA).

Legal Status: 4Cl-MDMB-BINACA is not currently a scheduled drug in the United States.

Class:

Cannabinoid

Appearance:

Transparent liquid

Formula:

C19H26ClN3O3

MW:

379.9

[M+]:

379

[M+H]+:

380.1735

IUPAC:

methyl 2-[[1-(4-chlorobutyl)indazole-3-carbonyl]amino]-3,3-dimethyl-butanoate

Report Date:

December 16, 2024